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Godley, Lucy
One or more keywords matched the following items that are connected to Godley, Lucy
Item TypeName
Concept Acute Disease
Concept Adenocarcinoma
Concept Acetylation
Concept Antibodies, Neoplasm
Concept Binding Sites, Antibody
Concept Breast Neoplasms
Concept Amino Acid Sequence
Concept Antigens, Differentiation
Concept Antigens, Surface
Concept Antineoplastic Agents
Concept Apolipoproteins E
Concept Busulfan
Concept Aneuploidy
Concept Animals
Concept Animals, Newborn
Concept Antifungal Agents
Concept Antimetabolites, Antineoplastic
Concept Antineoplastic Combined Chemotherapy Protocols
Concept Antiviral Agents
Concept Chromosomes, Human, Pair 6
Concept Analysis of Variance
Concept Antibodies, Monoclonal
Concept Ascorbic Acid
Concept Arabinonucleosides
Concept B-Lymphocytes
Concept Base Sequence
Concept Benzamides
Concept Cell Movement
Concept DNA Damage
Concept Bromelains
Concept Azacitidine
Concept Binding Sites
Concept Blood Grouping and Crossmatching
Concept California
Concept Cell Division
Concept Colon
Concept Colonic Neoplasms
Concept Cell Transformation, Neoplastic
Concept Uterine Cervical Neoplasms
Concept Chromosome Deletion
Concept Chromosomes, Human, Pair 22
Concept Burkitt Lymphoma
Concept Chromosomes, Human, Pair 5
Concept Chromosomes, Human, Pair 7
Concept C-Reactive Protein
Concept Cocarcinogenesis
Concept Hepatic Veno-Occlusive Disease
Concept Colony-Forming Units Assay
Concept DNA-Binding Proteins
Concept Immunosuppressive Agents
Concept Leukemia, Erythroblastic, Acute
Concept DNA Repair
Concept Drosophila
Concept Cause of Death
Concept DNA Mutational Analysis
Concept DNA, Neoplasm
Concept Cyclophosphamide
Concept Europe
Concept Glucocorticoids
Concept Graft Survival
Concept Enzyme Inhibitors
Concept Leukemia
Concept Chromosomes, Human, Pair 9
Concept Mammary Neoplasms, Experimental
Concept Expert Testimony
Concept Cytarabine
Concept Disease Susceptibility
Concept DNA
Concept DNA Topoisomerases, Type II
Concept Infant, Newborn
Concept Introns
Concept Methyltransferases
Concept Muscle Hypotonia
Concept Glioma
Concept Glioblastoma
Concept Feasibility Studies
Concept Fibroblast Growth Factors
Concept Karyotyping
Concept Graft Rejection
Concept DNA (Cytosine-5-)-Methyltransferases
Concept Hippocampus
Concept Heart
Concept Dose-Response Relationship, Drug
Concept Hydrogen Peroxide
Concept Histocompatibility Testing
Concept Hydroxamic Acids
Concept Flow Cytometry
Concept Fluorescent Antibody Technique
Concept Inflammation
Concept Infusions, Intravenous
Concept Genetics, Medical
Concept Length of Stay
Concept Hemagglutinins, Viral
Concept Lymphocyte Depletion
Concept Mammary Glands, Animal
Concept Hyperplasia
Concept Microcephaly
Concept Microfilament Proteins
Concept Models, Molecular
Concept Monoclonal Gammopathy of Undetermined Significance
Concept Pilot Projects
Concept Mice, Transgenic
Concept Neutropenia
Concept Mammary Tumor Virus, Mouse
Concept Mastocytosis
Concept Illinois
Concept Immunoglobulin Isotypes
Concept Pancreatic Neoplasms
Concept Mesoderm
Concept Mice, Inbred BALB C
Concept Mice, Inbred C57BL
Concept Mice, Nude
Concept Repetitive Sequences, Nucleic Acid
Concept Mitogens
Concept Mitoxantrone
Concept Morbidity
Concept Cricetinae
Concept Neutrophils
Concept L-Lactate Dehydrogenase
Concept Lactobacillus
Concept Ovarian Neoplasms
Concept Paraproteins
Concept Mediastinal Neoplasms
Concept Melphalan
Concept Membrane Fusion
Concept Morpholines
Concept Muscle Proteins
Concept Fibrosis
Concept Plasma Cells
Concept Protein Conformation
Concept Protease Inhibitors
Concept Histocompatibility Antigens
Concept HLA Antigens
Concept Recurrence
Concept Receptors, Cell Surface
Concept Registries
Concept Risk Factors
Concept Quality of Life
Concept Intestinal Mucosa
Concept Respiratory Tract Infections
Concept Cohort Studies
Concept Genes, ras
Concept Regulatory Sequences, Nucleic Acid
Concept Cadherins
Concept Interleukin-6
Concept Risk
Concept Sensitivity and Specificity
Concept Texas
Concept Sheep
Concept Humans
Concept Leukemia, Mast-Cell
Concept Leukemia, Radiation-Induced
Concept Leukocyte Count
Concept Incidence
Concept Cluster Analysis
Concept Bone Marrow Transplantation
Concept Tretinoin
Concept Superoxides
Concept United States
Concept Syndrome
Concept Caenorhabditis elegans
Concept Kidney Failure, Chronic
Concept Germ-Line Mutation
Concept Leukemia, Lymphocytic, Chronic, B-Cell
Concept Geriatric Assessment
Concept Leukemia, Myeloid
Concept Hematopoietic Stem Cell Transplantation
Concept Rett Syndrome
Concept Proportional Hazards Models
Concept Risk Assessment
Concept Disease Management
Concept Insect Proteins
Concept Myeloablative Agonists
Concept Nuclear Localization Signals
Concept Reverse Transcriptase Polymerase Chain Reaction
Concept Vidarabine
Concept Models, Animal
Concept Receptors, Colony-Stimulating Factor
Concept Central Nervous System Neoplasms
Concept HMGA2 Protein
Concept DNA Modification Methylases
Concept Bias
Concept Prevalence
Concept Metabolic Clearance Rate
Concept Zebrafish Proteins
Concept Antigens, CD
Concept Lymphoma
Concept Mitochondria
Concept Mortality
Concept Multiple Myeloma
Concept Leukemia, Myeloid, Acute
Concept CD4-Positive T-Lymphocytes
Concept Stem Cell Transplantation
Concept Mutagenesis, Site-Directed
Concept Tacrolimus
Concept Case-Control Studies
Concept Antigens, Nuclear
Concept In Situ Hybridization
Concept Sequence Analysis, DNA
Concept Protein Structure, Tertiary
Concept Community-Acquired Infections
Concept Methylation
Concept Treatment Outcome
Concept Neoplasm Metastasis
Concept Neoplasm Recurrence, Local
Concept Neoplasms, Experimental
Concept Genomic Instability
Concept Oligodeoxyribonucleotides
Concept Consensus Sequence
Concept Point Mutation
Concept Bacteriophage T4
Concept Gene Deletion
Concept Sequence Deletion
Concept Mice, Knockout
Concept CD8-Positive T-Lymphocytes
Concept DNA, Complementary
Concept Antigens, CD34
Concept Disease Progression
Concept Telomerase
Concept Thrombospondin 1
Concept Wnt1 Protein
Concept beta Catenin
Concept Antineoplastic Agents, Alkylating
Concept Smad1 Protein
Concept Caspase 3
Concept Receptor Protein-Tyrosine Kinases
Concept Mutation, Missense
Concept Drosophila Proteins
Concept Lymphocyte Count
Concept CpG Islands
Concept In Situ Hybridization, Fluorescence
Concept Chromosomes, Artificial, Human
Concept Peripheral Blood Stem Cell Transplantation
Concept Intercellular Signaling Peptides and Proteins
Concept Myelopoiesis
Concept Karyopherins
Concept DNA Repair Enzymes
Concept Histone Code
Concept Microarray Analysis
Concept Response Elements
Concept Proto-Oncogene Proteins c-kit
Concept Oligonucleotide Array Sequence Analysis
Concept Amino Acid Motifs
Concept Catalytic Domain
Concept Databases, Genetic
Concept Cyclin-Dependent Kinase Inhibitor p21
Concept Wnt Proteins
Concept Phosphopyruvate Hydratase
Concept Postoperative Complications
Concept Promoter Regions, Genetic
Concept Mice
Concept Caspase 8
Concept Surveys and Questionnaires
Concept Severity of Illness Index
Concept RNA, Messenger
Concept Mastocytosis, Systemic
Concept Sulfonamides
Concept Transfer RNA Aminoacylation
Concept Donor Selection
Concept Chimerism
Concept Preoperative Period
Concept Tetrasomy
Concept GATA1 Transcription Factor
Concept Rats
Concept Kruppel-Like Transcription Factors
Concept Real-Time Polymerase Chain Reaction
Concept Antibodies, Monoclonal, Humanized
Concept Valproic Acid
Concept Adaptor Proteins, Signal Transducing
Concept Blotting, Western
Concept Protein Interaction Domains and Motifs
Concept Leukemia, Promyelocytic, Acute
Concept Toll-Like Receptor 2
Concept Survival Analysis
Concept Lentivirus
Concept DNA Copy Number Variations
Concept Lymphoma, B-Cell
Concept Reproducibility of Results
Concept Leukemia, Myelomonocytic, Chronic
Concept Gene Expression Regulation, Leukemic
Concept Survival Rate
Concept Codon, Nonsense
Concept Fusion Proteins, bcr-abl
Concept Lymphocyte Subsets
Concept Polymerase Chain Reaction
Concept Granulocyte Colony-Stimulating Factor
Concept Zinc Fingers
Concept Lymphoma, Large B-Cell, Diffuse
Concept CD3 Complex
Concept Leukemic Infiltration
Concept DNA Methylation
Concept Hemagglutinin Glycoproteins, Influenza Virus
Concept Karnofsky Performance Status
Concept Precursor Cell Lymphoblastic Leukemia-Lymphoma
Concept Validation Studies as Topic
Concept Xenograft Model Antitumor Assays
Concept Germinal Center
Concept Cell Lineage
Concept Hematologic Neoplasms
Concept Histone Demethylases
Concept Histone Deacetylase Inhibitors
Concept alpha Karyopherins
Concept Tandem Repeat Sequences
Concept Acute Kidney Injury
Concept DNA Mismatch Repair
Concept Genome-Wide Association Study
Concept Precision Medicine
Concept Haploinsufficiency
Concept Multiplex Polymerase Chain Reaction
Concept RNA, Small Interfering
Concept Cord Blood Stem Cell Transplantation
Concept Molecular Sequence Annotation
Concept Microfluidics
Concept Tissue Array Analysis
Concept Methyl-CpG-Binding Protein 2
Concept Myeloid-Lymphoid Leukemia Protein
Concept fms-Like Tyrosine Kinase 3
Concept Kaplan-Meier Estimate
Concept Induced Pluripotent Stem Cells
Concept Asymptomatic Diseases
Concept Chromosome Aberrations
Concept Clinical Trials as Topic
Concept Cytosine
Concept Disease Models, Animal
Concept Doxorubicin
Concept Enhancer Elements, Genetic
Concept Follow-Up Studies
Concept Genetic Counseling
Concept Genetic Testing
Concept Hemoglobinuria, Paroxysmal
Concept Injections, Subcutaneous
Concept Liver Diseases
Concept Lymphocyte Activation
Concept Lymphoma, Non-Hodgkin
Concept Mice, Mutant Strains
Concept Models, Biological
Concept Monocytes
Concept Neoplasm Invasiveness
Concept Neuroblastoma
Concept Predictive Value of Tests
Concept Prospective Studies
Concept Histone-Lysine N-Methyltransferase
Concept Proto-Oncogenes
Concept Receptors, Antigen, T-Cell
Concept Retrospective Studies
Concept Staining and Labeling
Concept Translocation, Genetic
Concept World Health Organization
Concept Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Concept Immunophenotyping
Concept Granulocyte-Macrophage Colony-Stimulating Factor
Concept Cytokines
Concept Li-Fraumeni Syndrome
Concept Conserved Sequence
Concept DNA Primers
Concept Neoplasm, Residual
Concept Disease-Free Survival
Concept Chromosome Breakage
Concept Genetic Predisposition to Disease
Concept Polymorphism, Single Nucleotide
Concept Cytogenetic Analysis
Concept Databases, Nucleic Acid
Concept MicroRNAs
Concept Chromosomes, Human, X
Concept 5-Methylcytosine
Concept Protein Kinase Inhibitors
Concept Molecular Dynamics Simulation
Academic Article TTID: A novel gene at 5q31 encoding a protein with titin-like features.
Academic Article Molecular characterization of KLHL3, a human homologue of the Drosophila kelch gene.
Academic Article cDNA cloning and genomic structure of three genes localized to human chromosome band 5q31 encoding potential nuclear proteins.
Academic Article Expression profiling of CD34+ hematopoietic stem/ progenitor cells reveals distinct subtypes of therapy-related acute myeloid leukemia.
Academic Article Transcript map and comparative analysis of the 1.5-Mb commonly deleted segment of human 5q31 in malignant myeloid diseases with a del(5q).
Academic Article Successful autologous stem cell collection in patients with chronic myeloid leukemia in complete cytogenetic response, with quantitative measurement of BCR-ABL expression in blood, marrow, and apheresis products.
Academic Article Cancer cells express aberrant DNMT3B transcripts encoding truncated proteins.
Academic Article A phase I biological study of MG98, an oligodeoxynucleotide antisense to DNA methyltransferase 1, in patients with high-risk myelodysplasia and acute myeloid leukemia.
Academic Article Deletion of the der(9q) in chronic myeloid leukemia: the controversy continues.
Academic Article Allogeneic stem cell transplantation with alemtuzumab-based conditioning for patients with advanced chronic myelogenous leukemia.
Academic Article Epigenetic alterations differ in phenotypically distinct human neuroblastoma cell lines.
Academic Article Phase I study of dose-escalated busulfan with fludarabine and alemtuzumab as conditioning for allogeneic hematopoietic stem cell transplant: reduced clearance at high doses and occurrence of late sinusoidal obstruction syndrome/veno-occlusive disease.
Academic Article Patterns and kinetics of T-cell chimerism after allo transplant with alemtuzumab-based conditioning: mixed chimerism protects from GVHD, but does not portend disease recurrence.
Academic Article Treatment of therapy-related myeloid neoplasms with high-dose cytarabine/mitoxantrone followed by hematopoietic stem cell transplant.
Academic Article Coordinated cancer germline antigen promoter and global DNA hypomethylation in ovarian cancer: association with the BORIS/CTCF expression ratio and advanced stage.
Academic Article Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation.
Academic Article Selective chemical labeling reveals the genome-wide distribution of 5-hydroxymethylcytosine.
Academic Article The use of hypomethylating agents in the treatment of hematologic malignancies.
Academic Article DNA methyltransferase 1 and DNA methylation patterning contribute to germinal center B-cell differentiation.
Academic Article High dose cytarabine and mitoxantrone: an effective induction regimen for high-risk acute myeloid leukemia (AML).
Academic Article Gene mutations, epigenetic dysregulation, and personalized therapy in myeloid neoplasia: are we there yet?
Academic Article Inhibition of TET2-mediated conversion of 5-methylcytosine to 5-hydroxymethylcytosine disturbs erythroid and granulomonocytic differentiation of human hematopoietic progenitors.
Academic Article TET2 inactivation results in pleiotropic hematopoietic abnormalities in mouse and is a recurrent event during human lymphomagenesis.
Academic Article Characterization of NOL7 gene point mutations, promoter methylation, and protein expression in cervical cancer.
Academic Article Truncated DNMT3B isoform DNMT3B7 suppresses growth, induces differentiation, and alters DNA methylation in human neuroblastoma.
Academic Article Molecular biology. Preference by exclusion.
Academic Article Tet2 loss leads to increased hematopoietic stem cell self-renewal and myeloid transformation.
Academic Article Effects of TET2 mutations on DNA methylation in chronic myelomonocytic leukemia.
Academic Article An integrated genomic approach to the assessment and treatment of acute myeloid leukemia.
Academic Article Dnmt3a is essential for hematopoietic stem cell differentiation.
Academic Article Epigenetic regulation of hypoxic sensing disrupts cardiorespiratory homeostasis.
Academic Article Identification and molecular characterization of a novel 3′ mutation in RUNX1 in a family with familial platelet disorder.
Academic Article 5-hmC-mediated epigenetic dynamics during postnatal neurodevelopment and aging.
Academic Article Profiles in leukemia.
Academic Article Wild-type p53 transgenic mice exhibit altered differentiation of the ureteric bud and possess small kidneys.
Academic Article Fludarabine, melphalan, and alemtuzumab conditioning in adults with standard-risk advanced acute myeloid leukemia and myelodysplastic syndrome.
Academic Article DNMT3B7, a truncated DNMT3B isoform expressed in human tumors, disrupts embryonic development and accelerates lymphomagenesis.
Academic Article Getting to the root of the stem cell in mutated chronic myeloid leukemia.
Academic Article T-cell-depleted allogeneic transplant without donor leukocyte infusions results in excellent long-term survival in patients with multiply relapsed Lymphoma. Predictors for survival after transplant relapse.
Academic Article Recurrent somatic TET2 mutations in normal elderly individuals with clonal hematopoiesis.
Academic Article Deficiency of p53 accelerates mammary tumorigenesis in Wnt-1 transgenic mice and promotes chromosomal instability.
Academic Article Defining the steps in a multistep mouse model for mammary carcinogenesis.
Academic Article Absence of p53 in a mouse mammary tumor model promotes tumor cell proliferation without affecting apoptosis.
Academic Article Identifying familial myelodysplastic/acute leukemia predisposition syndromes through hematopoietic stem cell transplantation donors with thrombocytopenia.
Academic Article High resolution methylome analysis reveals widespread functional hypomethylation during adult human erythropoiesis.
Academic Article Perspectives and future directions for epigenetics in hematology.
Academic Article Genome-wide variation of cytosine modifications between European and African populations and the implications for complex traits.
Academic Article 2-Hydroxyglutarate in IDH mutant acute myeloid leukemia: predicting patient responses, minimal residual disease and correlations with methylcytosine and hydroxymethylcytosine levels.
Academic Article Dnmt3b is a haploinsufficient tumor suppressor gene in Myc-induced lymphomagenesis.
Academic Article Proposal for the clinical detection and management of patients and their family members with familial myelodysplastic syndrome/acute leukemia predisposition syndromes.
Academic Article Histone-lysine methyltransferase EHMT2 is involved in proliferation, apoptosis, cell invasion, and DNA methylation of human neuroblastoma cells.
Academic Article Immune reconstitution after combined haploidentical and umbilical cord blood transplant.
Academic Article Perturbations of 5-hydroxymethylcytosine patterning in hematologic malignancies.
Academic Article Randomized open-label phase II study of decitabine in patients with low- or intermediate-risk myelodysplastic syndromes.
Academic Article Hydroxymethylation at gene regulatory regions directs stem/early progenitor cell commitment during erythropoiesis.
Academic Article TET1-mediated hydroxymethylation facilitates hypoxic gene induction in neuroblastoma.
Academic Article Genome-wide hydroxymethylation tested using the HELP-GT assay shows redistribution in cancer.
Academic Article Mechanism-based epigenetic chemosensitization therapy of diffuse large B-cell lymphoma.
Academic Article New themes in the biological functions of 5-methylcytosine and 5-hydroxymethylcytosine.
Academic Article Inherited predisposition to acute myeloid leukemia.
Academic Article DNA hydroxymethylation profiling reveals that WT1 mutations result in loss of TET2 function in acute myeloid leukemia.
Academic Article Alterations of 5-hydroxymethylcytosine in human cancers.
Academic Article Large conserved domains of low DNA methylation maintained by Dnmt3a.
Academic Article DNMT3B7 expression promotes tumor progression to a more aggressive phenotype in breast cancer cells.
Academic Article The role of gene body cytosine modifications in MGMT expression and sensitivity to temozolomide.
Academic Article Variability in DNA methylation defines novel epigenetic subgroups of DLBCL associated with different clinical outcomes.
Academic Article A new family with a germline ANKRD26 mutation and predisposition to myeloid malignancies.
Academic Article The mechanistic role of DNA methylation in myeloid leukemogenesis.
Academic Article Linking the genetic architecture of cytosine modifications with human complex traits.
Academic Article TET2 Mutations Affect Non-CpG Island DNA Methylation at Enhancers and Transcription Factor-Binding Sites in Chronic Myelomonocytic Leukemia.
Academic Article 5-hydroxymethylcytosine in cancer: significance in diagnosis and therapy.
Academic Article Characterization of CpG sites that escape methylation on the inactive human X-chromosome.
Academic Article DNA Methylation Dynamics of Germinal Center B Cells Are Mediated by AID.
Academic Article Genomic analysis of germ line and somatic variants in familial myelodysplasia/acute myeloid leukemia.
Academic Article TET-catalyzed 5-hydroxymethylcytosine regulates gene expression in differentiating colonocytes and colon cancer.
Academic Article Epigenetic Control of Apolipoprotein E Expression Mediates Gender-Specific Hematopoietic Regulation.
Academic Article Increased DNA methylation of Dnmt3b targets impairs leukemogenesis.
Academic Article Novel germ line DDX41 mutations define families with a lower age of MDS/AML onset and lymphoid malignancies.
Academic Article Fumarate and Succinate Regulate Expression of Hypoxia-inducible Genes via TET Enzymes.
Academic Article Corrigendum: TET-catalyzed 5-hydroxymethylcytosine regulates gene expression in differentiating colonocytes and colon cancer.
Academic Article Rigosertib versus best supportive care for patients with high-risk myelodysplastic syndromes after failure of hypomethylating drugs (ONTIME): a randomised, controlled, phase 3 trial.
Academic Article Incidence and predictors of respiratory viral infections by multiplex PCR in allogeneic hematopoietic cell transplant recipients 50 years and older including geriatric assessment.
Academic Article Erratum to "5-hydroxymethylcytosine in cancer: Significance in diagnosis and therapy" [Cancer Genet 208 (2015):167-177].
Academic Article Identifying Inherited and Acquired Genetic Factors Involved in Poor Stem Cell Mobilization and Donor-Derived Malignancy.
Academic Article Genetic predisposition to leukemia and other hematologic malignancies.
Academic Article Cytogenetic responses to a 5-day dosing schedule of decitabine in patients (Pts) with myelodysplastic syndromes (MDS).
Academic Article A multicenter phase II trial of the decitabine alternative 5-day dosing regimen: Analysis of efficacy in various subgroups of patients with myelodysplastic syndromes (MDS).
Academic Article Efficacy of single-agent decitabine in relapsed and refractory acute myeloid leukemia.
Academic Article Recognition of familial myeloid neoplasia in adults.
Academic Article Therapy-related myeloid neoplasms: when genetics and environment collide.
Academic Article Microbial signals drive pre-leukaemic myeloproliferation in a Tet2-deficient host.
Academic Article Prognostic tumor sequencing panels frequently identify germ line variants associated with hereditary hematopoietic malignancies.
Academic Article MBD4: guardian of the epigenetic galaxy.
Academic Article Altered hydroxymethylation is seen at regulatory regions in pancreatic cancer and regulates oncogenic pathways.
Academic Article Mitochondrial superoxide disrupts the metabolic and epigenetic landscape of CD4+ and CD8+ T-lymphocytes.
Academic Article Cytokine-Regulated Phosphorylation and Activation of TET2 by JAK2 in Hematopoiesis.
Academic Article Somatic mutation panels: Time to clear their names.
Academic Article 5-Hydroxymethylcytosine Profiles Are Prognostic of Outcome in Neuroblastoma and Reveal Transcriptional Networks That Correlate With Tumor Phenotype.
Academic Article FouNdER mutations confer risk for leukemias.
Academic Article 5-Hydroxymethylcytosine Profiles in Circulating Cell-Free DNA Associate with Disease Burden in Children with Neuroblastoma.
Academic Article A phase 1 study of azacitidine with high-dose cytarabine and mitoxantrone in high-risk acute myeloid leukemia.
Academic Article MYC Regulation of D2HGDH and L2HGDH Influences the Epigenome and Epitranscriptome.
Academic Article HIF-1 directly induces TET3 expression to enhance 5-hmC density and induce erythroid gene expression in hypoxia.
Academic Article Regulation of telomeric function by DNA methylation differs between humans and mice.
Academic Article Heterozygous germ line CSF3R variants as risk alleles for development of hematologic malignancies.
Academic Article Identifying potential germline variants from sequencing hematopoietic malignancies.
Academic Article Identifying potential germline variants from sequencing hematopoietic malignancies.
Academic Article RBL2 bi-allelic truncating variants cause severe motor and cognitive impairment without evidence for abnormalities in DNA methylation or telomeric function.
Academic Article The chemotherapeutic CX-5461 primarily targets TOP2B and exhibits selective activity in high-risk neuroblastoma.
Academic Article MYCN and HIF-1 directly regulate TET1 expression to control 5-hmC gains and enhance neuroblastoma cell migration in hypoxia.
Academic Article Germ line DDX41 mutations define a unique subtype of myeloid neoplasms.
Academic Article Single-cell multi-omics of human clonal hematopoiesis reveals that DNMT3A R882 mutations perturb early progenitor states through selective hypomethylation.
Academic Article Allogeneic hematopoietic stem cell transplant outcomes in adults with inherited myeloid malignancies.
Academic Article (R)-2-Hydroxyglutarate Inhibits KDM5 Histone Lysine Demethylases to Drive Transformation in IDH-Mutant Cancers.
Concept Clinical Decision-Making
Concept Imatinib Mesylate
Concept Filgrastim
Concept Bortezomib
Concept N-Myc Proto-Oncogene Protein
Concept MDS1 and EVI1 Complex Locus Protein
Concept Alemtuzumab
Concept CCCTC-Binding Factor
Concept Kruppel-Like Factor 6
Concept DNA (Cytosine-5-)-Methyltransferase 1
Concept Proteasome Inhibitors
Concept Polycomb Repressive Complex 2
Concept Carcinogenesis
Concept Connectin
Concept Patient-Specific Modeling
Grant The Role of DNMT3B in the DNA Methylation of Cancer Cells
Grant A chemical crosslinking strategy to determine DNA methylating protein complexes
Grant Epigenetic and Genetic Dissection of Drug Response
Search Criteria
  • DNA
  • Cytosine
  • 5
  • Methyltransferases